Updated May 2026
Publications
Peer-reviewed publications across statistical genetics, functional annotation, EBV epigenomics, host-pathogen biology, and biomedical data science.
Update note. The recent publication list was refreshed from PubMed records associated with ORCID 0000-0001-9382-5674, publisher-indexed records, and the existing site bibliography. Google Scholar remains linked for live citation metrics.
Selected
Representative publications
A short list for search committees and collaborators who need the main signal first.
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Nat Methods. 2022;19:1599-1611.
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
Nat Genet. 2020;52(9):969-983.
Epstein-Barr Virus Nuclear Antigen Leader Protein coactivates EP300.
J Virol. 2018;92(9):e02155-17.
The Epstein-Barr virus regulome in lymphoblastoid cells.
Cell Host Microbe. 2017;22(4):561-573.
Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions.
Biol Direct. 2014;9:5.
Full list
Chronological bibliography
Recent peer-reviewed records appear first, followed by earlier publications across genomics, epigenomics, and computational biology.
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Nat Methods. 2022;19:1599-1611.
A multi-dimensional integrative scoring framework for predicting functional variants in the human genome.
Am J Hum Genet. 2022;109(3):446-456.
AFA: ancestry-specific allele frequency estimation in admixed populations: the Hispanic Community Health Study/Study of Latinos.
Hum Genet Genom Adv. 2022;3(2):100096.
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.
Nat Genet. 2022;54(3):263-273.
Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study.
Sci Rep. 2022;12(1):1-11.
Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer.
Genet Epidemiol. 2021;45(1):99-114.
Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.
Genome Med. 2021;13(1):1-17.
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
Nat Genet. 2020;52(9):969-983.
Epstein-Barr virus episome physically interacts with active regions of the host genome in lymphoblastoid cells.
J Virol. 2020;94(24):e01390-20.
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Proc Natl Acad Sci U S A. 2020;117(5):2560-2569.
Dynamic scan procedure for detecting rare-variant association regions in whole-genome sequencing studies.
Am J Hum Genet. 2019;104(5):802-814.
Epstein-Barr Virus Nuclear Antigen Leader Protein coactivates EP300.
J Virol. 2018;92(9):e02155-17.
Haemophilus parasuis infection disrupts adherens junctions and initializes EMT dependent on canonical Wnt/beta-catenin signaling pathway.
Front Cell Infect Microbiol. 2018;8:324.
Haemophilus parasuis infection activates NOD1/2-RIP2 signaling pathway in PK-15 cells.
Dev Comp Immunol. 2018;79:158-165.
The Epstein-Barr virus regulome in lymphoblastoid cells.
Cell Host Microbe. 2017;22(4):561-573.
Nasopharyngeal carcinoma super-enhancer-driven ETV6 correlates with prognosis.
Proc Natl Acad Sci U S A. 2017;114(36):9683-9688.
Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies.
J Clin Invest. 2017;127(6):2066-2080.
Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease.
Proc Natl Acad Sci U S A. 2017;114(18):4751-4756.
Epstein-Barr virus super-enhancer eRNAs are essential for MYC oncogene expression and lymphoblast proliferation.
Proc Natl Acad Sci U S A. 2016;113(49):14121-14126.
Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A.
Proc Natl Acad Sci U S A. 2015;112(37):11612-11617.
The association between indwelling arterial catheters and mortality in hemodynamically stable patients with respiratory failure: a propensity score analysis.
Chest. 2015;148(6):1470-1476.
TRAF1 coordinates polyubiquitin signaling to enhance Epstein-Barr Virus LMP1-mediated growth and survival pathway activation.
PLoS Pathog. 2015;11(5):e1004890.
Epstein-Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexes.
Proc Natl Acad Sci U S A. 2015;112(2):554-559.
The NF-kappaB genomic landscape in lymphoblastoid B cells.
Cell Rep. 2014;8(5):1595-1606.
Epstein-Barr virus infection in Chinese children: a retrospective study of age-specific prevalence.
PLoS One. 2014;9(6):e99857.
Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions.
Biol Direct. 2014;9:5.
Epstein-Barr virus nuclear antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A.
Proc Natl Acad Sci U S A. 2014;111(1):421-426.
LipidGO: database for lipid-related GO terms and applications.
Bioinformatics. 2014;30(7):1043-1044.
Progress in computational studies of host-pathogen interactions.
J Bioinform Comput Biol. 2013;11(2):1230001.
IntPath: an integrated pathway gene relationship database for model organisms and important pathogens.
BMC Syst Biol. 2012;6 Suppl 2:S2.
Comparative analysis and assessment of M. tuberculosis H37Rv protein-protein interaction datasets.
BMC Genomics. 2011;12 Suppl 3:S20.
Transcriptional responses of Haemophilus parasuis to iron-restriction stress in vitro.
Biometals. 2009;22(6):907-916.