Updated May 2026

Publications

Peer-reviewed publications across statistical genetics, functional annotation, EBV epigenomics, host-pathogen biology, and biomedical data science.

Update note. The recent publication list was refreshed from PubMed records associated with ORCID 0000-0001-9382-5674, publisher-indexed records, and the existing site bibliography. Google Scholar remains linked for live citation metrics.

Google Scholar profile ORCID PubMed search

Selected

Representative publications

A short list for search committees and collaborators who need the main signal first.

2026

Scalable and accurate rare-variant association tests for whole genome sequencing time-to-event analysis in large biobanks.

Song S, Li X, Zhou H, Li Z, Lin X.

Proc Natl Acad Sci U S A. 2026;123(9):e2525288123.

2026

Comparison of variant callers using 60,532 multi-ancestry whole genome sequences.

Zhou H, Li Z, Shyr D, Li X, Yang H, Dey R, Tang Y, Maier R, Boerwinkle E, Buyske S, Daly M, Felsenfeld A, Gibbs RA, Gupta N, Hall IM, Matise T, Metcalf GA, Smith A, Reeves C, Sofia HJ, Stitziel NO, Zody MC, NHGRI Genome Sequencing Program Consortium, Neale B, Lin X.

Brief Bioinform. 2026;27(2).

2026

cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions.

Van Buren E, Zhang Y, Li X, Selvaraj MS, Li Z, Zhou H, Palmer ND, Arnett DK, Blangero J, Boerwinkle E, Cade BE, Carlson JC, Carson AP, Chen YI, Curran J, Duggirala R, Fornage M, Franceschini N, Graff M, Gu C, Guo X, He J, Heard-Cosa N, Hou L, Hung YJ, Kalyani RR, Kardia SLR, Kenny E, Kooperberg C, Kral BG, Lange L, Levy D, Li C, Liu S, Lloyd-Jones D, Loos RJF, Manichaikul AW, Martin LW, Mathias R, Minster RL, Mitchell BD, Mychaleckyj JC, Naseri T, North K, O'Connell J, Perry JA, Peyser PA, Psaty BM, Raffield LM, Vasan RS, Redline S, Reiner AP, Rich SS, Smith JA, Spitzer B, Tang H, Taylor KD, Tracy R, Viali S, Yanek L, Zhao W, NHLBI TOPMed Consortium, Rotter JI, Peloso GM, Natarajan P, Lin X.

Nat Methods. 2026;23(2):338-349.

2026

FAVOR 2.0: A reengineered functional annotation of variants online resource for interpreting genomic variation.

Zhou H, Verma V, Li X, Li Z, Shedd N, Li TC, Yang H, Zhang A, Borsari B, Buyske S, Gerstein M, Matise T, Zody MC, Neale B, Weng Z, Sunyaev SR, Lin X.

Nucleic Acids Res. 2026;54(D1):D1405-D1414.

2025

A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.

Li X, Chen H, Selvaraj MS, Van Buren E, Zhou H, Wang Y, Sun R, McCaw ZR, Yu Z, Jiang MZ, DiCorpo D, Gaynor SM, Dey R, Arnett DK, Benjamin EJ, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Carson AP, Carlson JC, Chami N, Chen YI, Curran JE, de Vries PS, Fornage M, Franceschini N, Freedman BI, Gu C, Heard-Costa NL, He J, Hou L, Hung YJ, Irvin MR, Kaplan RC, Kardia SLR, Kelly TN, Konigsberg I, Kooperberg C, Kral BG, Li C, Li Y, Lin H, Liu CT, Loos RJF, Mahaney MC, Martin LW, Mathias RA, Mitchell BD, Montasser ME, Morrison AC, Naseri T, North KE, Palmer ND, Peyser PA, Psaty BM, Redline S, Reiner AP, Rich SS, Sitlani CM, Smith JA, Taylor KD, Tiwari HK, Vasan RS, Viali S, Wang Z, Wessel J, Yanek LR, Yu B, NHLBI TOPMed Consortium, Dupuis J, Meigs JB, Auer PL, Raffield LM, Manning AK, Rice KM, Rotter JI, Peloso GM, Natarajan P, Li Z, Liu Z, Lin X.

Nat Comput Sci. 2025;5(2):125-143.

2024

FAVOR-GPT: a generative natural language interface to whole genome variant functional annotations.

Li TC, Zhou H, Verma V, Tang X, Shao Y, Van Buren E, Weng Z, Gerstein M, Neale B, Sunyaev SR, Lin X.

Bioinform Adv. 2024;4(1):vbae143.

2023

FAVOR: functional annotation of variants online resource and annotator for variation across the human genome.

Zhou H, Arapoglou T, Li X, Li Z, Zheng X, Moore J, Asok A, Kumar S, Blue EE, Buyske S, Cox N, Felsenfeld A, Gerstein M, Kenny E, Li B, Matise T, Philippakis A, Rehm HL, Sofia HJ, Snyder G, Weng Z, Neale B, Sunyaev SR, Lin X.

Nucleic Acids Res. 2023;51(D1):D1300-D1311.

2023

Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies.

Li X, Quick C, Zhou H, Gaynor SM, Liu Y, Chen H, Selvaraj MS, Sun R, Dey R, Arnett DK, Bielak LF, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Correa A, Cupples LA, Curran JE, de Vries PS, Duggirala R, Freedman BI, Goring HH, Guo X, Haessler J, Kalyani RR, Kooperberg C, Kral BG, Lange LA, Manichaikul A, Martin LW, McGarvey ST, Mitchell BD, Montasser ME, Morrison AC, Naseri T, O'Connell JR, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Reupena MS, Rice KM, Rich SS, Sitlani CM, Smith JA, Taylor KD, Vasan RS, Willer CJ, Wilson JG, Yanek LR, Zhao W, TOPMed Consortium, Rotter JI, Natarajan P, Peloso GM, Li Z, Lin X.

Nat Genet. 2023;55(1):154-164.

2022

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.

Li Z, Li X, Zhou H, Gaynor SM, Selvaraj MS, Arapoglou T, Quick C, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Auer PL, Bielak LF, Bis JC, Blackwell T, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Conomos MP, Correa A, Cupples LA, Curran JE, de Vries PS, Duggirala R, Franceschini N, Freedman BI, Goring HH, Guo X, Kalyani RR, Kooperberg C, Kral BG, Lange L, Lin B, Manichaikul A, Manning A, Martin LW, Mathias R, Meigs JB, Mitchell BD, Montasser ME, Morrison AC, Naseri T, O'Connell J, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Reupena MS, Rice KM, Rich S, Smith J, Taylor KD, Taub M, Vasan RS, Weeks D, Wilson J, Yanek L, Zhao W, TOPMed Group, Rotter J, Willer C, Natarajan P, Peloso G, Lin X.

Nat Methods. 2022;19:1599-1611.

2020

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.

Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Aslibekyan S, Ballantyne CM, Bielak LF, Blangero J, Boerwinkle E, Bowden DW, Broome JG, Conomos MP, Correa A, Cupples LA, Curran JE, Freedman BI, Guo X, Hindy G, Irvin MR, Kardia SLR, Kathiresan S, Khan AT, Kooperberg CL, Laurie CC, Liu XS, Mahaney MC, Manichaikul AW, Martin LW, Mathias RA, McGarvey ST, Mitchell BD, Montasser ME, Moore J, Morrison AC, O'Connell JR, Palmer ND, Pampana A, Peralta JM, Peyser PA, Psaty BM, Redline S, Rice KM, Rich SS, Smith JA, Tiwari HK, Tsai MY, Vasan RS, Wang FF, Weeks DE, Weng Z, Wilson JG, Yanek LR, TOPMed Consortium, Neale BM, Sunyaev SR, Abecasis GR, Rotter JI, Willer CJ, Peloso GM, Natarajan P, Lin X.

Nat Genet. 2020;52(9):969-983.

2018

Epstein-Barr Virus Nuclear Antigen Leader Protein coactivates EP300.

Wang C, Zhou H*, Xue Y, Liang J, Narita Y, Gerdt C, Zheng AY, Jiang R, Trudeau S, Peng CW, Gewurz BE.

J Virol. 2018;92(9):e02155-17.

2017

The Epstein-Barr virus regulome in lymphoblastoid cells.

Jiang S, Zhou H*, Liang J, Gerdt C, Wang C, Ke L, Schmidt SC, Narita Y, Ma Y, Wang S, Colson T.

Cell Host Microbe. 2017;22(4):561-573.

2015

Epstein-Barr virus oncoprotein super-enhancers control B cell growth.

Zhou H, Schmidt SC, Jiang S, Willox B, Bernhardt K, Liang J, Johannsen EC, Kharchenko P, Gewurz BE, Kieff E, Zhao B.

Cell Host Microbe. 2015;17(2):205-216.

2014

Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions.

Zhou H, Gao S, Nguyen NN, Fan M, Jin J, Liu B, Zhao L, Xiong G, Tan M, Li S, Wong L.

Biol Direct. 2014;9:5.

2013

Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2.

Portal D*, Zhou H*, Zhao B, Kharchenko PV, Lowry E, Wong L, Quackenbush J, Holloway D, Jiang S, Lu Y, Kieff E.

Proc Natl Acad Sci U S A. 2013;110(46):18537-18542.

Full list

Chronological bibliography

Recent peer-reviewed records appear first, followed by earlier publications across genomics, epigenomics, and computational biology.

2026

Scalable and accurate rare-variant association tests for whole genome sequencing time-to-event analysis in large biobanks.

Song S, Li X, Zhou H, Li Z, Lin X.

Proc Natl Acad Sci U S A. 2026;123(9):e2525288123.

2026

Comparison of variant callers using 60,532 multi-ancestry whole genome sequences.

Zhou H, Li Z, Shyr D, Li X, Yang H, Dey R, Tang Y, Maier R, Boerwinkle E, Buyske S, Daly M, Felsenfeld A, Gibbs RA, Gupta N, Hall IM, Matise T, Metcalf GA, Smith A, Reeves C, Sofia HJ, Stitziel NO, Zody MC, NHGRI Genome Sequencing Program Consortium, Neale B, Lin X.

Brief Bioinform. 2026;27(2).

2026

A multi-ancestry genetic reference for the Quebec population.

McClelland P, Femerling G, Laflamme R, Mejia-Garcia A, Sayahian Dehkordi M, Xiao H, Diaz-Papkovich A, Pelletier J, Grenier JC, Lo KS, Anderson-Trocme L, Bellavance J, Chapdelaine V, Gagnon G, De Mori A, Martinez G, Mohler K, de Malliard T, Labbe C, Labrecque M, Montpetit A, Spiegelman D, Rouleau GA, Theroux JF, Zhou H, Girard SL, Hussin JG, Laberge AM, Bherer C, Tetreault M, Gagliano Taliun SA, Taliun D, Gravel S, Lettre G.

Nat Commun. 2026;17(1):1319.

2026

cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions.

Van Buren E, Zhang Y, Li X, Selvaraj MS, Li Z, Zhou H, Palmer ND, Arnett DK, Blangero J, Boerwinkle E, Cade BE, Carlson JC, Carson AP, Chen YI, Curran J, Duggirala R, Fornage M, Franceschini N, Graff M, Gu C, Guo X, He J, Heard-Cosa N, Hou L, Hung YJ, Kalyani RR, Kardia SLR, Kenny E, Kooperberg C, Kral BG, Lange L, Levy D, Li C, Liu S, Lloyd-Jones D, Loos RJF, Manichaikul AW, Martin LW, Mathias R, Minster RL, Mitchell BD, Mychaleckyj JC, Naseri T, North K, O'Connell J, Perry JA, Peyser PA, Psaty BM, Raffield LM, Vasan RS, Redline S, Reiner AP, Rich SS, Smith JA, Spitzer B, Tang H, Taylor KD, Tracy R, Viali S, Yanek L, Zhao W, NHLBI TOPMed Consortium, Rotter JI, Peloso GM, Natarajan P, Lin X.

Nat Methods. 2026;23(2):338-349.

2026

FAVOR 2.0: A reengineered functional annotation of variants online resource for interpreting genomic variation.

Zhou H, Verma V, Li X, Li Z, Shedd N, Li TC, Yang H, Zhang A, Borsari B, Buyske S, Gerstein M, Matise T, Zody MC, Neale B, Weng Z, Sunyaev SR, Lin X.

Nucleic Acids Res. 2026;54(D1):D1405-D1414.

2025

Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium.

Dong M, Thakral A, Byrne KS, Bosse Y, Zhou H, Zhang Y, Atkins J, Haycock P, Brown MC, Murison K, Timens W, Sin DD, Kothari J, Gabriel AAG, Zaridze D, Savic M, Lissowska J, Swiatkowska B, Janout V, Holcatova I, Mukeria A, Fernandez-Tardon G, Davies MPA, Triplette M, Schabath MB, Andrew AS, Chen C, Taylor F, Field JK, Tardon A, Shete SS, Brennan P, Landi MT, McKay J, Amos CI, Lin X, Christiani DC, Hung RJ, Liu G, Xu W.

Carcinogenesis. 2025;46(2):bgaf031.

2025

A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.

Li X, Chen H, Selvaraj MS, Van Buren E, Zhou H, Wang Y, Sun R, McCaw ZR, Yu Z, Jiang MZ, DiCorpo D, Gaynor SM, Dey R, Arnett DK, Benjamin EJ, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Carson AP, Carlson JC, Chami N, Chen YI, Curran JE, de Vries PS, Fornage M, Franceschini N, Freedman BI, Gu C, Heard-Costa NL, He J, Hou L, Hung YJ, Irvin MR, Kaplan RC, Kardia SLR, Kelly TN, Konigsberg I, Kooperberg C, Kral BG, Li C, Li Y, Lin H, Liu CT, Loos RJF, Mahaney MC, Martin LW, Mathias RA, Mitchell BD, Montasser ME, Morrison AC, Naseri T, North KE, Palmer ND, Peyser PA, Psaty BM, Redline S, Reiner AP, Rich SS, Sitlani CM, Smith JA, Taylor KD, Tiwari HK, Vasan RS, Viali S, Wang Z, Wessel J, Yanek LR, Yu B, NHLBI TOPMed Consortium, Dupuis J, Meigs JB, Auer PL, Raffield LM, Manning AK, Rice KM, Rotter JI, Peloso GM, Natarajan P, Li Z, Liu Z, Lin X.

Nat Comput Sci. 2025;5(2):125-143.

2024

Deciphering the impact of genomic variation on function.

IGVF Consortium.

Nature. 2024;633(8028):47-57.

2024

Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height.

Hawkes G, Beaumont RN, Li Z, Mandla R, Li X, Albert CM, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Boerwinkle E, Brody JA, Carson AP, Chami N, Chen YI, Chung MK, Curran JE, Darbar D, Ellinor PT, Fornage M, Gordeuk VR, Guo X, He J, Hwu CM, Kalyani RR, Kaplan R, Kardia SLR, Kooperberg C, Loos RJF, Lubitz SA, Minster RL, Naseri T, Viali S, Mitchell BD, Murabito JM, Palmer ND, Psaty BM, Redline S, Shoemaker MB, Silverman EK, Telen MJ, Weiss ST, Yanek LR, Zhou H, NHLBI TOPMed Consortium, Liu CT, North KE, Justice AE, Locke JM, Owens N, Murray A, Patel K, Frayling TM, Wright CF, Wood AR, Lin X, Manning A, Weedon MN.

Nat Commun. 2024;15(1):8549.

2024

FAVOR-GPT: a generative natural language interface to whole genome variant functional annotations.

Li TC, Zhou H, Verma V, Tang X, Shao Y, Van Buren E, Weng Z, Gerstein M, Neale B, Sunyaev SR, Lin X.

Bioinform Adv. 2024;4(1):vbae143.

2024

Repurposing Type I-A CRISPR-Cas3 for a robust diagnosis of human papillomavirus (HPV).

Hu T, Ji Q, Ke X, Zhou H, Zhang S, Ma S, Yu C, Ju W, Lu M, Lin Y, Ou Y, Zhou Y, Xiao Y, Xu C, Hu C.

Commun Biol. 2024;7(1):858.

2023

FAVOR: functional annotation of variants online resource and annotator for variation across the human genome.

Zhou H, Arapoglou T, Li X, Li Z, Zheng X, Moore J, Asok A, Kumar S, Blue EE, Buyske S, Cox N, Felsenfeld A, Gerstein M, Kenny E, Li B, Matise T, Philippakis A, Rehm HL, Sofia HJ, Snyder G, Weng Z, Neale B, Sunyaev SR, Lin X.

Nucleic Acids Res. 2023;51(D1):D1300-D1311.

2023

Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies.

Li X, Quick C, Zhou H, Gaynor SM, Liu Y, Chen H, Selvaraj MS, Sun R, Dey R, Arnett DK, Bielak LF, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Correa A, Cupples LA, Curran JE, de Vries PS, Duggirala R, Freedman BI, Goring HH, Guo X, Haessler J, Kalyani RR, Kooperberg C, Kral BG, Lange LA, Manichaikul A, Martin LW, McGarvey ST, Mitchell BD, Montasser ME, Morrison AC, Naseri T, O'Connell JR, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Reupena MS, Rice KM, Rich SS, Sitlani CM, Smith JA, Taylor KD, Vasan RS, Willer CJ, Wilson JG, Yanek LR, Zhao W, TOPMed Consortium, Rotter JI, Natarajan P, Peloso GM, Li Z, Lin X.

Nat Genet. 2023;55(1):154-164.

2022

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.

Li Z, Li X, Zhou H, Gaynor SM, Selvaraj MS, Arapoglou T, Quick C, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Auer PL, Bielak LF, Bis JC, Blackwell T, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Conomos MP, Correa A, Cupples LA, Curran JE, de Vries PS, Duggirala R, Franceschini N, Freedman BI, Goring HH, Guo X, Kalyani RR, Kooperberg C, Kral BG, Lange L, Lin B, Manichaikul A, Manning A, Martin LW, Mathias R, Meigs JB, Mitchell BD, Montasser ME, Morrison AC, Naseri T, O'Connell J, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Reupena MS, Rice KM, Rich S, Smith J, Taylor KD, Taub M, Vasan RS, Weeks D, Wilson J, Yanek L, Zhao W, TOPMed Group, Rotter J, Willer C, Natarajan P, Peloso G, Lin X.

Nat Methods. 2022;19:1599-1611.

2022

A multi-dimensional integrative scoring framework for predicting functional variants in the human genome.

Li X, Yung G, Zhou H, Sun R, Li Z, Hou K, Zhang MJ, Liu Y, Arapoglou T, Wang C, Ionita-Laza I, Lin X.

Am J Hum Genet. 2022;109(3):446-456.

2022

AFA: ancestry-specific allele frequency estimation in admixed populations: the Hispanic Community Health Study/Study of Latinos.

Granot-Hershkovitz E, Sun Q, Argos M, Zhou H, Lin X, Browning SR, Sofer T.

Hum Genet Genom Adv. 2022;3(2):100096.

2022

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.

Wainschtein P, Jain D, Zheng Z, Cupples LA, Shadyab AH, McKnight B, Shoemaker BM, Mitchell BD, Psaty BM, Kooperberg C, Liu CT, et al.

Nat Genet. 2022;54(3):263-273.

2022

Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study.

Wang H, Kurniansyah N, Cade BE, Goodman MO, Chen H, Gottlieb DJ, Gharib SA, Purcell SM, Lin X, Saxena R, Zhu X.

Sci Rep. 2022;12(1):1-11.

2021

Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer.

Sun R, Xu M, Li X, Gaynor S, Zhou H, Li Z, Bosse Y, Lam S, Tsao MS, Tardon A, Chen C.

Genet Epidemiol. 2021;45(1):99-114.

2021

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.

Cade BE, Lee J, Sofer T, Wang H, Zhang M, Chen H, Gharib SA, Gottlieb DJ, Guo X, Lane JM, Liang J, et al.

Genome Med. 2021;13(1):1-17.

2020

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.

Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Aslibekyan S, Ballantyne CM, Bielak LF, Blangero J, Boerwinkle E, Bowden DW, Broome JG, Conomos MP, Correa A, Cupples LA, Curran JE, Freedman BI, Guo X, Hindy G, Irvin MR, Kardia SLR, Kathiresan S, Khan AT, Kooperberg CL, Laurie CC, Liu XS, Mahaney MC, Manichaikul AW, Martin LW, Mathias RA, McGarvey ST, Mitchell BD, Montasser ME, Moore J, Morrison AC, O'Connell JR, Palmer ND, Pampana A, Peralta JM, Peyser PA, Psaty BM, Redline S, Rice KM, Rich SS, Smith JA, Tiwari HK, Tsai MY, Vasan RS, Wang FF, Weeks DE, Weng Z, Wilson JG, Yanek LR, TOPMed Consortium, Neale BM, Sunyaev SR, Abecasis GR, Rotter JI, Willer CJ, Peloso GM, Natarajan P, Lin X.

Nat Genet. 2020;52(9):969-983.

2020

Epstein-Barr virus episome physically interacts with active regions of the host genome in lymphoblastoid cells.

Wang L, Laing J, Yan B, Zhou H, Ke L, Wang C, Narita Y, Zhang Z, Olson MR, Afzali B, Zhao B.

J Virol. 2020;94(24):e01390-20.

2020

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.

Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedon JC, et al.

Proc Natl Acad Sci U S A. 2020;117(5):2560-2569.

2019

Dynamic scan procedure for detecting rare-variant association regions in whole-genome sequencing studies.

Li Z, Li X, Liu Y, Shen J, Chen H, Zhou H, Morrison AC, Boerwinkle E, Lin X.

Am J Hum Genet. 2019;104(5):802-814.

2018

Epstein-Barr Virus Nuclear Antigen Leader Protein coactivates EP300.

Wang C, Zhou H*, Xue Y, Liang J, Narita Y, Gerdt C, Zheng AY, Jiang R, Trudeau S, Peng CW, Gewurz BE.

J Virol. 2018;92(9):e02155-17.

2018

Haemophilus parasuis infection disrupts adherens junctions and initializes EMT dependent on canonical Wnt/beta-catenin signaling pathway.

Hua K, Li Y, Zhou H, Hu X, Chen Y, He R, Luo R, Zhou R, Bi D, Jin H.

Front Cell Infect Microbiol. 2018;8:324.

2018

Haemophilus parasuis infection activates NOD1/2-RIP2 signaling pathway in PK-15 cells.

Ma B, Hua K, Zhou S, Zhou H, Chen Y, Luo R, Bi D, Zhou R, He Q, Jin H.

Dev Comp Immunol. 2018;79:158-165.

2017

The Epstein-Barr virus regulome in lymphoblastoid cells.

Jiang S, Zhou H*, Liang J, Gerdt C, Wang C, Ke L, Schmidt SC, Narita Y, Ma Y, Wang S, Colson T.

Cell Host Microbe. 2017;22(4):561-573.

2017

Nasopharyngeal carcinoma super-enhancer-driven ETV6 correlates with prognosis.

Ke L, Zhou H, Wang C, Xiong G, Xiang Y, Ling Y, Khabir A, Tsao GS, Zeng Y, Zeng M, Busson P.

Proc Natl Acad Sci U S A. 2017;114(36):9683-9688.

2017

Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies.

Nayar U, Sadek J, Reichel J, Hernandez-Hopkins D, Akar G, Barelli PJ, Sahai MA, Zhou H, Totonchy J, Jayabalan D, Niesvizky R.

J Clin Invest. 2017;127(6):2066-2080.

2017

Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease.

Minamitani T, Ma Y, Zhou H, Kida H, Tsai CY, Obana M, Okuzaki D, Fujio Y, Kumanogoh A, Zhao B, Kikutani H.

Proc Natl Acad Sci U S A. 2017;114(18):4751-4756.

2016

Epstein-Barr virus super-enhancer eRNAs are essential for MYC oncogene expression and lymphoblast proliferation.

Liang J, Zhou H, Gerdt C, Tan M, Colson T, Kaye KM, Kieff E, Zhao B.

Proc Natl Acad Sci U S A. 2016;113(49):14121-14126.

2015

Epstein-Barr virus oncoprotein super-enhancers control B cell growth.

Zhou H, Schmidt SC, Jiang S, Willox B, Bernhardt K, Liang J, Johannsen EC, Kharchenko P, Gewurz BE, Kieff E, Zhao B.

Cell Host Microbe. 2015;17(2):205-216.

2015

Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A.

Minamitani T, Yasui T, Ma Y, Zhou H, Okuzaki D, Tsai CY, Sakakibara S, Gewurz BE, Kieff E, Kikutani H.

Proc Natl Acad Sci U S A. 2015;112(37):11612-11617.

2015

The association between indwelling arterial catheters and mortality in hemodynamically stable patients with respiratory failure: a propensity score analysis.

Hsu DJ, Feng M, Kothari R, Zhou H, Chen KP, Celi LA.

Chest. 2015;148(6):1470-1476.

2015

TRAF1 coordinates polyubiquitin signaling to enhance Epstein-Barr Virus LMP1-mediated growth and survival pathway activation.

Greenfeld H, Takasaki K, Walsh MJ, Ersing I, Bernhardt K, Ma Y, Fu B, Ashbaugh CW, Cabo J, Mollo SB, Zhou H, Li S, Gewurz BE.

PLoS Pathog. 2015;11(5):e1004890.

2015

Epstein-Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexes.

Schmidt SC, Jiang S, Zhou H, Willox B, Holthaus AM, Kharchenko PV, Johannsen EC, Kieff E, Zhao B.

Proc Natl Acad Sci U S A. 2015;112(2):554-559.

2014

The NF-kappaB genomic landscape in lymphoblastoid B cells.

Zhao B, Barrera LA, Ersing I, Willox B, Schmidt SC, Greenfeld H, Zhou H, Mollo SB, Shi TT, Takasaki K, Jiang S, Cahir-McFarland E, Kellis M, Bulyk ML, Kieff E, Gewurz BE.

Cell Rep. 2014;8(5):1595-1606.

2014

Epstein-Barr virus infection in Chinese children: a retrospective study of age-specific prevalence.

Xiong G, Zhang B, Huang MY, Zhou H, Chen LZ, Feng QS, Luo X, Lin HJ, Zeng YX.

PLoS One. 2014;9(6):e99857.

2014

Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions.

Zhou H, Gao S, Nguyen NN, Fan M, Jin J, Liu B, Zhao L, Xiong G, Tan M, Li S, Wong L.

Biol Direct. 2014;9:5.

2014

Epstein-Barr virus nuclear antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A.

Jiang S, Willox B, Zhou H, Holthaus AM, Wang A, Shi TT, Maruo S, Kharchenko PV, Johannsen EC, Kieff E, Zhao B.

Proc Natl Acad Sci U S A. 2014;111(1):421-426.

2014

LipidGO: database for lipid-related GO terms and applications.

Fan M, Low HS, Zhou H, Wenk MR, Wong L.

Bioinformatics. 2014;30(7):1043-1044.

2013

Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2.

Portal D*, Zhou H*, Zhao B, Kharchenko PV, Lowry E, Wong L, Quackenbush J, Holloway D, Jiang S, Lu Y, Kieff E.

Proc Natl Acad Sci U S A. 2013;110(46):18537-18542.

2013

Progress in computational studies of host-pathogen interactions.

Zhou H, Jin J, Wong L.

J Bioinform Comput Biol. 2013;11(2):1230001.

2012

IntPath: an integrated pathway gene relationship database for model organisms and important pathogens.

Zhou H, Jin J, Zhang H, Yi B, Wozniak M, Wong L.

BMC Syst Biol. 2012;6 Suppl 2:S2.

2011

Comparative analysis and assessment of M. tuberculosis H37Rv protein-protein interaction datasets.

Zhou H, Wong L.

BMC Genomics. 2011;12 Suppl 3:S20.

2009

Transcriptional responses of Haemophilus parasuis to iron-restriction stress in vitro.

Xie Q, Jin H, Luo R, Wan Y, Chu J, Zhou H, Shi B, Chen H, Zhou R.

Biometals. 2009;22(6):907-916.